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产品名称: |
Beta-Catenin |
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中国大陆 |
访问次数: |
1902 |
发布时间: |
2016/3/28 16:25:01 |
Beta-catenin is a component of the adherens junction, a multiprotein complex which supports Ca2+ -dependent cell to cell contact which in itself is critical for adhesion
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Beta-Catenin Clone 17C2 7 mL BOND ready-to-use PA0083 P (HIER) Antigen Background The catenins, (alpha, beta and gamma) are cytoplasmic proteins which bind to the highly conserved tail of the E-cadherin molecule. Beta-catenin is a component of the adherens junction, a multiprotein complex which supports Ca2+ -dependent cell to cell contact which in itself is critical for adhesion, signal transmission and for anchoring the actin cytoskeleton. Beta-catenin’s role is as a transcription effector of the wnt-signalling pathway. Immunohistochemistry is the best way to demonstrate nuclear expression of betacatenin and wnt-pathway activation. This aberrant expression is observed in human tumorigenesis and especially in colorectal cancer. Also available as a liquid concentrate, refer to page 100
Colon polyp: immunohistochemical staining with BOND ready-to-use Beta-Catenin (17C2) using BOND Polymer Refine Detection.
更新时间:2024/4/3 14:23:06 标签: Clone 17C2 抗体 二抗体
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